94683-55-3Relevant academic research and scientific papers
SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins
Yan, Su,Elmes, Matthew W.,Tong, Simon,Hu, Kongzhen,Awwa, Monaf,Teng, Gary Y.H.,Jing, Yunrong,Freitag, Matthew,Gan, Qianwen,Clement, Timothy,Wei, Longfei,Sweeney, Joseph M.,Joseph, Olivia M.,Che, Joyce,Carbonetti, Gregory S.,Wang, Liqun,Bogdan, Diane M.,Falcone, Jerome,Smietalo, Norbert,Zhou, Yuchen,Ralph, Brian,Hsu, Hao-Chi,Li, Huilin,Rizzo, Robert C.,Deutsch, Dale G.,Kaczocha, Martin,Ojima, Iwao
, p. 233 - 252 (2018/05/28)
Fatty acid binding proteins (FABPs) serve as critical modulators of endocannabinoid signaling by facilitating the intracellular transport of anandamide and whose inhibition potentiates anandamide signaling. Our previous work has identified a novel small-m
α-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF
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Page/Page column 55, (2017/09/27)
The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure : Formula (I)
The photodimerisation of the chloro-, methoxy- and nitro-derivatives of trans-cinnamic acid: A study of single crystals by vibrational microspectroscopy
Atkinson, Samantha D. M.,Almond, Matthew J.,Bowmaker, Graham A.,Drew, Michael G. B.,Feltham, Emma J.,Hollins, Peter,Jenkins, Samantha L.,Wiltshire, Karen S.
, p. 1533 - 1537 (2007/10/03)
The techniques of infrared and Raman microscopy have been used to monitor the photochemical dimerisation reactions of β-2-chloro-trans-cinnamic acid, β-3-chloro-trans-cinnamic acid, β-4-chloro-trans-cinnamic acid, α-2-methoxy-trans-cinnamic acid, β-2-nitro-trans-cinnamic acid, β-3-nitro-trans-cinnamic acid and β-4-nitro-trans-cinnamic acid. In this way the topotactic nature of the reactions has been confirmed. These reactive derivatives have been compared with the unreactive γ-forms of these and related compounds.
Radiation-induced reactions via the lowest excited states in cinnamic acid crystals
Maekawa, Yasunari,Inaba, Tomonori,Hobo, Hiroki,Narita, Tadashi,Koshikawa, Hiroshi,Moon, Seongyun,Kato, Jun,Yoshida, Masaru
, p. 2088 - 2089 (2007/10/03)
Radiation-induced reactions of cinnamic acid derivatives have been examined and compared with photoreactions in the crystalline state; all the reaction products were exactly the same as those of the photoreactions, indicating that the reactions proceed only via the lowest excited state to give [2 + 2] cycloadducts, E/Z isomerization products, or starting molecules.
Solid-State Photoreactivity of Ethyl (E)-α-Cyano-2-methoxycinnamate
Chimichi, Stefano,Sarti-Fantoni, Piero,Coppini, Giacomo,Perghem, Franca,Renzi, Giovanni
, p. 5124 - 5126 (2007/10/02)
The reinvestigation of the solid-state photoreactivity of ethyl (E)-α-cyano-2-methoxycinnamate (1) allowed us to obtain the corresponding dimer which was shown to be diethyl (1α,2α,3β,4β)-1,3-dicyano-2,4-bis(2-methoxyphenyl)cyclobutane-1,3-dicarboxylate (
