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946846-83-9

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946846-83-9 Usage

Description

Piromelatine is a novel investigational agent that has agonist activity at MT1 and MT2 along with agonism at 5-HT1A/1D receptors. A phase II randomized clinical trial (N 1/4 120) in primary insomnia resulted in significant improvement in insomnia symptoms.

Clinical claims and research

Piromelatine known as Neu-P11 is a newer melatonin receptor agonist underdevelopmental stage. It acts on MT1, MT2, and also 5-HT1A/5- HT1D receptors. It has demonstrated improvement in the sleep cycle of primary insomnia patients and reducing sleep disturbances in Phase II clinical trial. It was found to have efficacy in maintaining deeper sleep, less arousal, and also preserving REM sleep pattern. In the clinical trial, piromelatine was well tolerated with no adverse effects on psychomotor performance the following day (She et al., 2014).

Check Digit Verification of cas no

The CAS Registry Mumber 946846-83-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,8,4 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 946846-83:
(8*9)+(7*4)+(6*6)+(5*8)+(4*4)+(3*6)+(2*8)+(1*3)=229
229 % 10 = 9
So 946846-83-9 is a valid CAS Registry Number.

946846-83-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxopyran-2-carboxamide

1.2 Other means of identification

Product number -
Other names NEU-P11

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:946846-83-9 SDS

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