946856-59-3

Basic information

• Product Name: C₂₂H₂₆N₄O₃
• CAS NO: 946856-59-3
• Molecular Weight: 394.473
• Mol File: 946856-59-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₆N₄O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₆N₄O₃(946856-59-3)
• EPA Substance Registry System: C₂₂H₂₆N₄O₃(946856-59-3)

Safety Data

• Hazardous Substances Data: 946856-59-3(Hazardous Substances Data)

Upstream product

• 946856-58-2 5-[2-ethoxyphenyl]-1-methyl-7-chloro-3-propyl-1H-pyrazolo[4,3-d]pyrimidine 
• 123-54-6 acetylacetone 

Downstream Products

• 1006061-73-9 3-[5-(2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl]-2,4-dimethyl-3H-1,5-benzodiazepine 

Relevant articles and documents

Synthesis, spectral studies and biological activity of novel 3H-1,5-benzodiazepine derivatives

Chlorination of 5-(2-ethoxyphenyl)-1-methyl-3-propyl-1, 6-dihydro-7H-pyrazolo [4, 3-d] pyrimidin-7-one 1 with POCl3 affords 5-(2-ethoxyphenyl)-1-methyl-7-chloro-1H-pyrazolo [4, 3-d] pyrimidine 2. Further compound 2 is condensed with different β-diketones / β-ketoesters3a-e, to obtain new β-diketones/β-ketoesters 4a-e. The synthesized new β-diketones/β-ketoesters (4a-e) and o-phenylenediamine (o-PDA) gives biologically active 3H-1,5-benzodiazepines 5a-e. All the newly synthesized compounds are characterized by elemental analysis and spectral studies. The compounds 5a-e have been screened for antimicrobial, antifungal and anthelmintic activity.