947-14-8 Usage
Uses
Used in Pharmaceutical Research:
Phenylacetone-d5 is used as a labeled metabolite for Lisdexamfetamine dimesylate, a psychostimulant medication. It serves as a valuable research tool in studying the metabolism and pharmacokinetics of the drug, providing insights into its mechanism of action and potential side effects.
Used in Chemical Synthesis:
Phenylacetone-d5 is utilized as a starting material or intermediate in the synthesis of various organic compounds. Its unique deuterium-labeled structure allows for the tracking of chemical reactions and the elucidation of reaction mechanisms, which is particularly useful in the development of new pharmaceuticals and other chemical products.
Used in Analytical Chemistry:
Phenylacetone-d5 is employed as an internal standard in analytical chemistry, particularly in techniques such as gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS). Its distinct isotopic signature enables accurate quantification and identification of target compounds, improving the reliability and precision of analytical results.
Used in Stable Isotope Tracing:
Phenylacetone-d5 is used in stable isotope tracing studies to investigate metabolic pathways and enzyme mechanisms. The incorporation of deuterium atoms allows researchers to track the movement and transformation of the compound within biological systems, providing valuable information on metabolic processes and potential drug interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 947-14-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,4 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 947-14:
(5*9)+(4*4)+(3*7)+(2*1)+(1*4)=88
88 % 10 = 8
So 947-14-8 is a valid CAS Registry Number.
947-14-8Relevant academic research and scientific papers
Oxidation of benzyl alcohols by dimethyldioxirane. The question of concerted versus stepwise mechanisms probed by kinetic isotope effects
Angelis, Yiannis S.,Hatzakis, Nikos S.,Smonou, Ioulia,Orfanopoulos, Michael
, p. 3753 - 3756 (2007/10/03)
The primary and β-secondary kinetic isotope effects in the oxidation of secondary alcohols with dimethyl dioxirane were measured. The substantial primary and the absence of a β-secondary kinetic isotope effect support a concerted mechanism for the title reaction.
