947159-65-1Relevant academic research and scientific papers
3-Arylamino-2H-1,2,4-benzothiadiazin-5-ol 1,1-dioxides as novel and selective CXCR2 antagonists
Wang, Yonghui,Busch-Petersen, Jakob,Wang, Feng,Ma, Lanping,Fu, Wei,Kerns, Jeffrey K.,Jin, Jian,Palovich, Michael R.,Shen, Jing-Kang,Burman, Miriam,Foley, James J.,Schmidt, Dulcie B.,Hunsberger, Gerald E.,Sarau, Henry M.,Widdowson, Katherine L.
, p. 3864 - 3867 (2007)
A series of 3-arylamino-2H-1,2,4-benzothiadiazin-5-ol 1,1-dioxides were prepared and shown to be novel and selective antagonists of the CXCR2 receptor. Synthesis, structure and activity relationships, selectivity, and some developability properties are described.
