94752-74-6Relevant academic research and scientific papers
Metal- and Oxidant-Free Alkenyl C?H/Aromatic C?H Cross-Coupling Using Electrochemically Generated Iodosulfonium Ions
Hayashi, Ryutaro,Shimizu, Akihiro,Davies, Jonathan A.,Ishizaki, Yu,Willis, Chris,Yoshida, Jun-ichi
supporting information, p. 12891 - 12895 (2018/09/14)
A three-step transformation consisting of 1) addition of electrochemically generated iodosulfonium ions to vinylarenes to give (1-aryl-2-iodoethoxy)sulfonium ions, 2) nucleophilic substitution by subsequently added aromatic compounds to give 1,1-diaryl-2-
Branched Arylalkenes from Cinnamates: Selectivity Inversion in Heck Reactions by Carboxylates as Deciduous Directing Groups
Tang, Jie,Hackenberger, Dagmar,Goossen, Lukas J.
supporting information, p. 11296 - 11299 (2016/10/13)
A decarboxylative Mizoroki–Heck coupling of aryl halides with cinnamic acids has been developed in which the carboxylate group directs the arylation into its β-position before being tracelessly removed through protodecarboxylation. In the presence of a copper/palladium catalyst, both electron-rich and electron-deficient aryl bromides and chlorides bearing numerous functionalities were successfully coupled with broadly available cinnamates, with selective formation of 1,1-disubstituted alkenes. This reaction concept, in which the carboxylate acts as a deciduous directing group, ideally complements traditional 1,2-selective Heck reactions of styrenes.
Synthesis of 1,1-diarylethylenes
Chang, Meng-Yang,Huang, Yi-Hsuan,Wang, Heui-Sin
, p. 3022 - 3031 (2016/05/19)
A facile route toward 1,1-diarylethylenes 6 has been developed in good yields via mCPBA-promoted oxidation of β-hydroxysulfides 2, BF3·OEt2-mediated Friedel-Crafts reaction of the resulting β-hydroxysulfoxides 3 with oxygenated benze
