94753-46-5Relevant academic research and scientific papers
Mechanism of an unusual decarboxylative cyclization
Kende, Andrew S.,Henry, Olivier,Chen, Zecheng
, p. 7809 - 7812 (2004)
The mechanism of an unusual decarboxylative cyclization from 5-methoxy-1-(2-carboxyphenyl)-1,4-dihydro-4-oxopyridine-2-carboxylic acid (diacid) to 3-methoxypyrido[1,2-a]indole-2,10-dione (ketone) has been investigated. 13C-labeling has demonstrated that the carbonyl carbon of the ketone arises exclusively from the anthranilic acid carboxyl of the diacid. A zwitterionic mechanism has been proposed.
