947530-20-3Relevant academic research and scientific papers
Diastereoselective synthesis of 2-monosubstituted and 2,6-disubstituted piperidines
Abrunhosa-Thomas, Isabelle,Roy, Olivier,Barra, Marielle,Besset, Tatiana,Chalard, Pierre,Troin, Yves
, p. 1613 - 1615 (2008/02/05)
An intramolecular Michael-type reaction, involving β′-amino- α,β-unsaturated ketone is used to prepare 2-mono- and 2,6-disusbtituted piperidines in a diastereoselective manner. This strategy allows an easy access to 2,6-trans-piperidine, starting from eit
