947618-07-7 Usage
Uses
Used in Medicinal Chemistry:
(S)-2-2-[2-(diphenylphosphino)phenyl]propan-2-yl-4-tert-butyl-4,5-dihydrooxazole is used as a building block for the synthesis of pharmaceuticals and natural products due to its oxazole core and the potential biological activities associated with this class of compounds.
Used in Organic Chemistry:
In the field of organic chemistry, (S)-2-2-[2-(diphenylphosphino)phenyl]propan-2-yl-4-tert-butyl-4,5-dihydrooxazole is used as a synthetic intermediate or catalyst, leveraging the unique chemical and reactivity properties conferred by the diphenylphosphino substituent.
Used in Catalyst Development:
(S)-2-2-[2-(diphenylphosphino)phenyl]propan-2-yl-4-tert-butyl-4,5-dihydrooxazole is used as a catalyst in various chemical reactions, taking advantage of its unique structural features and reactivity to enhance the efficiency and selectivity of these processes.
Check Digit Verification of cas no
The CAS Registry Mumber 947618-07-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,7,6,1 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 947618-07:
(8*9)+(7*4)+(6*7)+(5*6)+(4*1)+(3*8)+(2*0)+(1*7)=207
207 % 10 = 7
So 947618-07-7 is a valid CAS Registry Number.
947618-07-7Relevant academic research and scientific papers
Wu, Wen-Qiong,Peng, Qian,Dong, Da-Xuan,Hou, Xue-Long,Wu, Yun-Dong
, p. 9717 - 9725 (2008)
A series of benzylic substituted P,N-ligands 1 and 2 have been synthesized. The Pd-complexes of these ligands show high catalytic activity and enantioselectivity in catalyzing the asymmetric Heck reaction. A dramatic switch in enantioselectivity is realized using ligands with and without substituents at the benzylic position of the ligand. Ligands 1 with H as the substituents offer products in (R)-configuration while ligands 2 with the methyl as substituents result in (S)-configuration products. In most cases high enantioselectivities are achieved. Density functional theory calculations on the reaction mechanism as well as X-ray analysis of 1a-PdCl2 and 2a-PdCl2 complexes provide a rational explanation for the above observations.
