947623-54-3Relevant academic research and scientific papers
Synthesis of the oxa-bridged octalin system of two anti-anaerobe antibiotics, luminamicin and lustromycin
Sunazuka, Toshiaki,Handa, Masaki,Hirose, Tomoyasu,Matsumaru, Takanori,Togashi, Yuko,Nakamura, Kaoru,Iwai, Yuzuru,Omura, Satoshi
, p. 5297 - 5300 (2008/02/09)
An efficient, stereocontrolled entry to the 11-oxatricyclo[5.3.1.1,703,8]undecane nucleus of luminamicin and lustromycin was afforded via intramolecular hetero-Michael addition of enone 7 followed by intramolecular aldol condensation of aldehyde 5 by way of the epimerization at the stereocenter attached by the aldehyde group.
