947682-59-9

Upstream product

• 380886-34-0 (2S,3S)-tert-butyl 2-hydroxy-3-methylpentanoate 
• 380886-49-7 tert-butyl (2S)-acetyloxy-(3S)-methylpentanoate 
• 73-32-5 L-isoleucine 
• 947682-90-8 (2S,3S)-tert-butyl 2-(((S)-2-(((2S,3R)-2-(((benzyloxy)carbonyl)amino)-3-((tertbutyldimethylsilyl)oxy)butanoyl)oxy)propanoyl)oxy)-3-methylpentanoate 
• 19728-63-3 N-benzyloxycarbonyl-L-treonine 
• 947682-60-2 (2S,3S)-tert-butyl 2-(((S)-2-hydroxypropanoyl)oxy)-3-methylpentanoate 
• 947682-89-5 (2S,3S)-tert-butyl 2-(((S)-2-((tert-butyldimethylsilyl)oxy)propanoyl)oxy)-3-methylpentanoate 

Downstream Products

• 1599436-60-8 C₃₇H₅₆N₂O₁₃*C₂HF₃O₂ 
• 947682-98-6 ((2S,5S,8S,13S,16R,17S)-5-((S)-sec-butyl)-8,13-diisobutyl-2,10,10,16-tetramethyl-3,6,9,11,14,18-hexaoxo-1,4,12,15-tetraoxa-7-azacyclooctadecan-17-yl)carbamate 
• 1599436-54-0 N-((2S,5S,8S,13S,16R,17S)-5-((S)-sec-butyl)-8,13-diisobutyl-2,10,10,16-tetramethyl-3,6,9,11,14,18-hexaoxo-1,4,12,15-tetraoxa-7-azacyclooctadecan-17-yl)-2-hydroxy-3-nitrobenzamide 
• 1599436-46-0 (S)-(5S,8S,11S,12R,15S)-11-(((benzyloxy)carbonyl)amino)-5-((S)-sec-butyl)-2,2,8,12,17-pentamethyl-4,7,10,14-tetraoxo-3,6,9,13-tetraoxaoctadecan-15-yl 4-((tertbutoxycarbonyl)amino)-2,2,6-trimethyl-3-oxoheptanoate 

Relevant academic research and scientific papers

An organotrifluoroborate-based convergent total synthesis of the potent cancer cell growth inhibitory depsipeptides kitastatin and respirantin

The total syntheses of the highly cytotoxic neo-antimycin macrocyclic depsipeptide natural products kitastatin and respirantin have been accomplished in a convergent manner using MNBA promoted esterifications and an efficient C- and N-terminus bis-deprote