947690-02-0Relevant articles and documents
Synthesis and biological activity of azido analogues of 5,6-dimethylxanthenone-4-acetic acid for use in photoaffinity labeling
Palmer, Brian D.,Henare, Kimiora,Woon, See-Tarn,Sutherland, Rachel,Reddy, Charu,Wang, Liang-Chuan S.,Kieda, Claudine,Ching, Lai-Ming
, p. 3757 - 3764 (2007)
5,6-Dimethylxanthenone-4-acetic acid (1) is scheduled for phase III clinical trials as a vascular disrupting agent. However, its biochemical receptor(s) have yet to be identified. In this report, the synthesis of azido analogues of 1 that could be used fo