947739-62-0Relevant academic research and scientific papers
Unprecedented reaction between ethyl α-cyanocinnamate and o-phenylenediamine: Development of an efficient method for the transfer hydrogenation of electronically depleted olefins
Kumar, Satish,Kapoor, Kamal K.
, p. 2809 - 2814 (2007)
A reaction between ethyl α-cyanocinnamate and o-phenylenediamine under thermal conditions yielded 2-cyano-3-phenyl-propionic acid ethyl ester, 2-phenyl benzimidazole, and ethyl cyanoacetate. The mechanistic revelations led to the development of a simple and efficient transfer-hydrogenation process from the in situ generated benzimidazolines to activated olefins under solventless and catalyst-free conditions. Georg Thieme Verlag Stuttgart.
Synthesis, in vitro anticancer activity and in silico study of new disubstituted thiazolidinedione derivatives
Rego, Moacyr Jesus Barreto De Melo,Galdino-Pitta, Marina Rocha,Pereira, Daniel Tarciso Martins,Da Silva, Juliana Cruz,Rabello, Marcelo Montenegro,Alves De Lima, Maria Do Carmo,Hernandes, Marcelo Zaldini,Da Rocha Pitta, Ivan,Galdino, Suely Lins,Da Rocha Pitta, Maira Galdino
, p. 3220 - 3226 (2014/05/06)
Thiazolidinediones are known to have antidiabetic activity, but new activities are being discovered every year; among these, their anticancer activity has received the most attention. In this study, we synthesized three new disubstituted thiazolidinedione
