947753-65-3

Basic information

• Product Name: 2,2-DIBROMO-5,6-DIFLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE
• Synonyms: 2,2-DIBROMO-5,6-DIFLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE
• CAS NO: 947753-65-3
• Molecular Formula: C9H4Br2F2O
• Molecular Weight: 0
• Mol File: 947753-65-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-DIBROMO-5,6-DIFLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIBROMO-5,6-DIFLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE(947753-65-3)
• EPA Substance Registry System: 2,2-DIBROMO-5,6-DIFLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE(947753-65-3)

Safety Data

• Hazardous Substances Data: 947753-65-3(Hazardous Substances Data)

Upstream product

• 161712-77-2 5,6-difluoroindan-1-one 

Relevant articles and documents

Simple and regioselective bromination of 5,6-disubstituted-indan-1-ones with Br2 under acidic and basic conditions

Bromination of 5,6-dimethoxyindan-1-one with Br2 in acetic acid at room temperature produced exclusively the corresponding 2,4-dibromo compound in 95% yield. Reaction of 5,6-dimethoxyindan-1-one with Br2 in the presence of KOH, K2CO3 or Cs2CO3 at ～0°C gave the monobrominated product 4-bromo-5,6-dimethoxyindan-3-one in 79%, 81% and 67% yield, respectively. 5,6-Dihydroxyindan-1-one was dibrominated on the aromatic ring affording 4,7-dibromo-5,6-dihydroxyindan-1-one both in acetic acid at room temperature and in the presence of KOH at ～0° C. 5,6-Difluoroindan-1-one and 1-indanone were α-monobrominated in acetic acid and α,aα-dibrominated under KOH conditions at room temperature.