947771-07-5

Basic information

• Product Name: 5-oxazolmethyl cyanide
• Synonyms: 5-oxazolmethyl cyanide;2-(oxazol-5-yl)acetonitrile
• CAS NO: 947771-07-5
• Molecular Formula: C₅H₄N₂O
• Molecular Weight: 108
• Mol File: 947771-07-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-oxazolmethyl cyanide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-oxazolmethyl cyanide(947771-07-5)
• EPA Substance Registry System: 5-oxazolmethyl cyanide(947771-07-5)

Safety Data

• Hazardous Substances Data: 947771-07-5(Hazardous Substances Data)

Upstream product

• 172649-57-9 5-(chloromethyl)oxazole 
• 143-33-9 sodium cyanide 
• 773837-37-9 sodium cyanide 

Relevant articles and documents

HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS

ABSTRACT The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.

Total synthesis of potent antifungal marine bisoxazole natural products bengazoles A and B

The bengazoles are a family of marine natural products that display potent antifungal activity and a unique structure, containing two oxazole rings flanking a single carbon atom. Total syntheses of bengazole A and B are described, which contain a sensitive stereogenic centre at this position between the two oxazolcs. Additionally, the synthesis of 10-epi-bengazole A is reported. Two parallel synthetic routes were investigated, relying on construction of the 2,4-disubstituted oxazole under mild conditions and a diastereoselective 1,3-dipolar cycloaddition. Our successful route is high yielding, provides rapid access to single stereoisomers of the complex natural products and allows the synthesis of analogues for biological evaluation.