948017-31-0

Upstream product

• 112906-84-0 2-[4-(2-hydroxyethoxy)benzylidene]malononitrile 
• 108-98-5 thiophenol 
• 109-77-3 malononitrile 
• 22042-73-5 4-(2-hydroxy-ethoxy)-benzaldehyde 

Downstream Products

• 1107662-79-2 2-Amino-6-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}-4-[4-(2-hydroxyethoxy)phenyl]-pyridine-3,5-dicarbonitrile 
• 1163272-51-2 2-Chloro-6-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}-4-[4-(2-hydroxyethoxy)phenyl]-pyridine-3,5-dicarbonitrile 
• 1163272-54-5 Methyl N-(6-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}-3,5-dicyano-4-[4-(2-hydroxyethoxy)phenyl]pyridin-2-yl)-N-methylglycinate 
• 1163271-04-2 Methyl 3-amino-6-{[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methoxy}-5-cyano-4-[4-(2-hydroxyethoxy)phenyl]-1-methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate 
• 1107663-71-7 6-Amino-4-[4-(2-hydroxyethoxy)phenyl]-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile 
• 1107662-82-7 2-Amino-6-{[2-(4-fluorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile 
• 1353656-35-5 3-[({6-amino-3,5-dicyano-4-[4-(2-hydroxyethoxy)phenyl]pyridin-2-yl}oxy)methyl]benzene-carboxylic acid 
• 1353657-22-3 4-[4-(2-hydroxyethoxy)phenyl]-2-sulfanylpyridine-3,5-dicarbonitrile 
• 1353657-37-0 4-[4-(2-hydroxyethoxy)phenyl]-2-(phenylthio)pyridine-3,5-dicarbonitrile 
• 1353656-82-2 4-[({6-amino-3,5-dicyano-4-[4-(2-hydroxyethoxy)phenyl]pyridin-2-yl}oxy)methyl]-N-methyl-pyridine-2-carboxamide 
• 948017-32-1 2-chloro-4-[4-(2-hydroxyethoxy)phenyl]-6-phenylthio-pyridine-3,5-dicarbonitrile 

Relevant academic research and scientific papers

SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF

The present application relates to novel substituted dicyanopyridines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prophylaxis of cardiovascular disorders.

SUBSTITUTED ARYLOXAZOLES AND THEIR USE

The present application relates to novel substituted aryloxazole derivatives, a method for the production thereof, the use thereof for the treatment and/or prophylaxis of diseases and the use thereof for the production of drugs for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular and metabolic disorders.

SUBSTITUTED AZABICYCLIC COMPOUNDS AND THE USE THEREOF

The present application relates to novel substituted pyrrolopyridine, pyrazolopyridine and isoxazolopyridine derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, preferably for the treatment and/or prevention of cardiovascular disorders.

Use of Adenosine A1 and/or Dual A1/2ab Agonists for Production of Medicaments for Treating Diseases

The present invention relates to the use of A1 and/or dual A1/A2b agonists of the formulae (IA) and (IB) for preparing a medicament for treating dyslipidemia, metabolic syndrome and diabetes and dyslipidemia, metabolic syndrome and diabetes in association with hypertension and cardiovascular disorders.

Substituted Phenylaminothiazoles and Use Thereof

The present application relates to novel phenylaminothiazole derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of hypertension and other cardiovascular disorders.

SUBSTITUTED PHENYLAMINOTHIAZOLES AND USE THEREOF

The invention relates to novel phenylaminothiazole derivatives, methods for the production thereof, the use thereof for treating and/or preventing diseases, and the use thereof for producing medicaments used for treating and/or preventing diseases, preferably hypertension and other cardiovascular diseases.