948027-08-5Relevant academic research and scientific papers
Homochiral coordination polymers with nanotubular channels for enantioselective sorption of chiral guest molecules
Tanaka, Koichi,Kikumoto, Yuki,Hota, Naoki,Takahashi, Hiroki
, p. 880 - 883 (2014)
Two novel chiral coordination polymers were synthesized by treating C 2-symmetric 2,2′-dihydroxy- and 2,2′-dimethoxy-1, 1′-binaphthalene-3,3′-dicarboxylic acids with Cu2+, in which sorption of some chiral β-lactam compounds in the fr
HPLC enantioseparation on a homochiral MOF-silica composite as a novel chiral stationary phase
Tanaka, Koichi,Muraoka, Toshihide,Otubo, Yasuhiro,Takahashi, Hiroki,Ohnishi, Atsushi
, p. 21293 - 21301 (2016/03/08)
The last frontier in the development of chiral stationary phases for chromatographic enantioseparation involves homochiral metal-organic frameworks (MOFs). Using enantiopure (R)-2,2′-dihydroxy-1,1′-binaphthalene-6,6′-dicarboxylic acid as a starting material, we prepared three homochiral MOFs that were further used as chiral stationary phases for high-performance liquid chromatography to separate the enantiomers of various kinds of racemic sulfoxides, sec-alcohols, β-lactams, benzoins, flavanones and epoxides. The experimental results showed excellent performances for enantioseparation, and highlighted that enantioseparation on homochiral MOF columns is practical.
