948039-07-4Relevant academic research and scientific papers
De novo synthesis of uronic acid building blocks for assembly of heparin oligosaccharides
Adibekian, Alexander,Bindschaedler, Pascal,Timmer, Mattie S. M.,Noti, Christian,Schuetzenmeister, Nina,Seeberger, Peter H.
, p. 4510 - 4522 (2008/02/08)
An efficient de novo synthesis of uronic acid building blocks is described. The synthetic strategy relies on the stereoselective elongation of thio-acetal protected dialdehydes 12a and 17. The dialdehydes are prepared from D-xylose, a cheap and commercial
Short de novo synthesis of fully functionalized uronic acid monosaccharides
Timmer, Mattie S. M.,Adibekian, Alexander,Seeberger, Peter H.
, p. 7605 - 7607 (2007/10/03)
(Chemical Equation Presented) Short and Sweet: A convergent route leads to orthogonally protected D-glucuronic and L-iduronic acid thioglycoside building blocks, commonly used in heparin oligosaccharide assembly (see scheme). Rapid access to substantial q
