948049-27-2

Upstream product

• 948049-33-0 (1S,2R,3R,4R,5R)-2,3,4-triacetoxy-N-(N-phenylcarbamoyl)-6-oxa-nor-tropane 
• 714967-59-6 3-O-acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-allofuranose 
• 714967-64-3 3,6-di-O-acetyl-5-azido-5-deoxy-1,2-O-isopropylidene-β-L-talofuranose 
• 29474-72-4 3-O-acetyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 714967-60-9 3-O-acetyl-5-azido-5-deoxy-1,2-O-isopropylidene-β-L-talofuranose 
• 2595-05-3 Diacetone D-glucose 
• 51433-05-7 3'-O-acetyl-1',2'-O-isopropylidene-5',6'-diol-α-D-allofuranose 
• 948049-31-8 (1S,2R,3S,4R,5R)-2,4-diacetoxy-3-benzyloxy-N-(N-phenylcarbamoyl)-6-oxa-nor-tropane 
• 948049-32-9 (1S,2R,3S,4R,5R)-3,4-diacetoxy-2-hydroxy-N-(N-phenylcarbamoyl)-6-oxa-nor-tropane 
• 714967-66-5 3,6-di-O-acetyl-5-deoxy-1,2-O-isopropylidene-5-(N'-phenylureido)-β-L-talofuranose 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 6-oxa-nor-tropane glycomimetics as glycosidase inhibitors

The preparation of polyhydroxylated 6-oxa-nor-tropane glycomimetics structurally related to the glycosidase inhibitor family of the calystegines is reported. The synthetic strategy involves the furanose→piperidine rearrangement of 5-deoxy-5-ureido-l-idose

Synthesis of calystegine B2, B3, and B4 analogues: Mapping the structure-glycosidase inhibitory activity relationships in the 1-deoxy-6-oxacalystegine series

A practical synthesis of ring-modified calystegine analogues with a 6-oxa-nor-tropane structure has been developed. The methodology relies on the ability of the masked carbonyl group of hexose precursors to act as the electrophilic target for the nitrogen