94805-85-3

Basic information

• Product Name: melongoside F
• Synonyms: melongoside F
• CAS NO: 94805-85-3
• Molecular Formula: C₃₉H₆₂O₁₃
• Molecular Weight: 738.90178
• Mol File: 94805-85-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 872.7°Cat760mmHg
• Flash Point: 481.6°C
• Appearance: /
• Density: 1.38g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: melongoside F(CAS DataBase Reference)
• NIST Chemistry Reference: melongoside F(94805-85-3)
• EPA Substance Registry System: melongoside F(94805-85-3)

Safety Data

• Hazardous Substances Data: 94805-85-3(Hazardous Substances Data)

Usage

General Description

Melongoside F is a chemical compound found in the roots of Melongena Spp. It belongs to a class of natural products called cucurbitane glycosides, which are known for their potential therapeutic properties. Melongoside F has been studied for its anti-inflammatory, antitumor, and antiviral activities, as well as its potential to lower blood glucose levels. It has been suggested that melongoside F may offer potential health benefits, and further research is being conducted to explore its medicinal properties.

InChI:InChI=1/C39H62O13/c1-18-7-12-39(47-17-18)19(2)28-25(52-39)14-24-22-6-5-20-13-21(8-10-37(20,3)23(22)9-11-38(24,28)4)48-36-34(32(45)30(43)27(16-41)50-36)51-35-33(46)31(44)29(42)26(15-40)49-35/h5,18-19,21-36,40-46H,6-17H2,1-4H3/t18-,19+,21?,22?,23?,24?,25+,26-,27-,28+,29-,30-,31+,32+,33-,34-,35+,36-,37+,38+,39?/m1/s1

Upstream product

• 89202-79-9 C₆₃H₉₀O₂₆ 
• 89203-43-0 melongoside H 
• 1019843-09-4 diosgenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1->2)-4,6-O-benzylidene-3-O-pivaloyl-β-D-glucopyranoside 
• 259882-10-5 diosgenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1->2)-4,6-O-benzylidene-β-D-glucopyranoside 
• 211797-89-6 diosgenyl 4,6-O-benzylidene-β-D-glucopyranoside 
• 74808-10-9 O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)trichloroacetimidate 

Downstream Products

• 470-05-3 diosgenin 
• 14144-06-0 trillin 
• 2280-44-6 D-Glucose 

Relevant articles and documents

Synthesis of novel spirostanic saponins and their cytotoxic activity

This study was carried out to assess the cytotoxicity of several new synthetic steroidal saponins against the human myeloid leukemia cell lines (HL-60 and U937) and against human melanoma cells (SK-MEL-1). Several diosgenyl glycosides analyzed showed strong cell growth inhibition which was associated with alterations in cell cycle progression and induction of apoptosis. Studies of cytochrome c release and caspase-9 activation suggest a main role of the intrinsic pathway of apoptosis in the mechanism of cytotoxicity caused by this kind of compounds.

STEROID GLYCOSIDES OF THE SEEDS OF Solanum melongena. STRUCTURES OF MELONGOSIDES A, B, E, F, AND H

Three chromatographically individual fractions, each containing tigogenin glycosides and diosgenin glycosides have been isolated by chromatography on a silica gel column from a methanolic extract of eggplant seeds.To separate the mixture of two difficultly separable glycosides into individual components, each fraction was acetylated and epoxidated, and the derivatives obtained were separated chromatographically.The tigogenin glycoside peracetates isolated were saponified, and the diosgenin epoxide glycoside acetates were de-epoxidated and saponified, to give the individual glycosides, melongosides A, B, E, F, and H.The complete chemical structure of each melongoside has been shown with the aid of acid hydrolysis, methylation, and periodate oxidation followed by a study of the products obtained.