948162-56-9Relevant academic research and scientific papers
Novel and efficient synthesis of pyrazolo]3,4-b]pyridin-6-ones or their hydrogenated derivatives through one-pot reaction in ionic liquid
Zhang, Xin-Ying,Li, Xiao-Yan,Fan, Xue-Sen,Wang, Xia,Qu, Gui-Rong,Wang, Jian-Ji
experimental part, p. 923 - 936 (2009/09/30)
Pyrazolo[3,4-b]pyridin-6-ones or their hydrogenated derivatives were obtained selectively and conveniently through one-pot reaction of aldehyde, ethyl cyanoacetate and 5-amino-3-methyl-1-phenylpyrazole in [bmim][BF4] with or without ferric chlo
An alternative preparation of pyrazolo-pyridine derivatives in ionic liquid and comparison study on the reactivity of thioamide and amide group
Zhang, Xin-Ying,Li, Xiao-Yan,Fan, Xue-Sen,Wang, Xia,Qu, Gui-Rong,Wang, Jian-Ji
scheme or table, p. 3065 - 3075 (2009/05/27)
A novel and efficient preparation of pyrazolo[3,4-b]pyridine (5) and pyrazolo[3,4-b]pyridin-6-one (8) derivatives from the condensation of arylidenecyanothioacetamide (1) or arylidenecyanoacetamide (7) with 5-amino-3-methyl-1-phenylpyrazole (4) in [bmim]BF4 is reported for the first time. The mechanism for the formation of 5 from 1 and 4, or 8 from 7 and 4, and the comparison between the reactivity of thioamide group versus amide group are briefly discussed.
