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GTP-GAMMA-S TETRALITHIUM SALT is a modified form of guanosine triphosphate (GTP), a nucleotide that plays a crucial role in cellular processes. GTP-GAMMA-S TETRALITHIUM SALT features a gamma-thio modification, which allows it to bind to G proteins and maintain them in an active state. This unique property makes it a valuable tool in various research applications.

94825-44-2

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94825-44-2 Usage

Uses

Used in Biochemical Research:
GTP-GAMMA-S TETRALITHIUM SALT is used as a research tool for studying the function and regulation of G proteins, which are involved in signal transduction pathways in cells. By keeping G proteins in a constantly active state, researchers can gain insights into their role in cellular signaling.
Used in Lysis Buffer:
In the context of oocyte and mammalian cell patch-clamp experiments, GTP-GAMMA-S TETRALITHIUM SALT is used as a component of lysis buffer. This helps in the disruption of cell membranes, allowing for the study of ion channels and other cellular components.
Used in G-Protein Alpha Coupling Studies:
GTP-GAMMA-S TETRALITHIUM SALT is used to couple with G-protein alpha subunits in order to study their effect on kinase activity. This application aids in understanding the intricate relationships between G proteins, kinases, and their roles in cellular processes.

Biochem/physiol Actions

GTP-γ-S is a non-hydrolyzable GTP analog, known for its role as a G-protein activator. It has recently been shown to protect proteins from proteolytic degradation, stimulate GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization in vitro.

Check Digit Verification of cas no

The CAS Registry Mumber 94825-44-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,8,2 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 94825-44:
(7*9)+(6*4)+(5*8)+(4*2)+(3*5)+(2*4)+(1*4)=162
162 % 10 = 2
So 94825-44-2 is a valid CAS Registry Number.

94825-44-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Sigma

  • (G8634)  Guanosine 5′-[γ-thio]triphosphate tetralithium salt  ≥75% (HPLC), powder

  • 94825-44-2

  • G8634-1MG

  • 752.31CNY

  • Detail
  • Sigma

  • (G8634)  Guanosine 5′-[γ-thio]triphosphate tetralithium salt  ≥75% (HPLC), powder

  • 94825-44-2

  • G8634-5MG

  • 2,458.17CNY

  • Detail
  • Sigma

  • (G8634)  Guanosine 5′-[γ-thio]triphosphate tetralithium salt  ≥75% (HPLC), powder

  • 94825-44-2

  • G8634-10MG

  • 3,498.30CNY

  • Detail
  • Sigma

  • (G8634)  Guanosine 5′-[γ-thio]triphosphate tetralithium salt  ≥75% (HPLC), powder

  • 94825-44-2

  • G8634-25MG

  • 8,488.35CNY

  • Detail

94825-44-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tetralithium,[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate

1.2 Other means of identification

Product number -
Other names EINECS 305-606-1

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:94825-44-2 SDS

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