948296-29-5

Upstream product

• 56264-07-4 4-chloro-1-(4-methoxyphenyloxy)but-2-yne 
• 89109-17-1 4-hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one 

Downstream Products

• 1018067-20-3 C₂₅H₂₀N₂O₃S 

Relevant academic research and scientific papers

Regioselective synthesis of pentacyclic polyheterocycles: Sequential [3,3] sigmatropic rearrangement of 4-(4′-aryloxybut-2′-ynyloxy)-1-phenyl- 1,8-naphthyridin-2(1H)-ones

(Chemical Equation Presented) A number of 4-aryloxymethyl-6-phenyl-2H- pyrano[3,2-c][1,8]naphthyridin-5(6H)-ones (4a-f) are regioselectively synthesized in 72-78% yield by the Claisen rearrangement of 4-(4′- aryloxybut-2′-ynyloxy)-1-phenyl-1,8-naphthyridi

Aluminium chloride-catalyzed claisen rearrangement: Synthesis of polyheterocycles containing oxygen, nitrogen, and sulfur

Synthesis of 1,8-naphthyridine-annulated polyheterocycles containing oxygen, nitrogen, and sulfur has been achieved by thionation and sequential Claisen rearrangement of 4-(4'-aryloxybut-2'-ynyloxy)-1-phenyl[1,8]- naphthyridin-2-ones first by heating in 1,2-dichlorobenzene for 1-2 h and then by anhydrous AlCl3-catalyzed Claisen rearrangement in dichloromethane for 1 h. Copyright Taylor & Francis Group, LLC.