94832-06-1

Basic information

• Product Name: 1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE
• Synonyms: 1-BROMO-4-METHYLSULFONYL-2-NITROBENZENE;1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE;2-BROMO-5-METHYLSULFONYLNITROBENZENE;1-Bromo-4-(methylsulphonyl)-2-nitrobenzene 98%;1-Bromo-4-(methylsulphonyl)-2-nitrobenzene98%
• CAS NO: 94832-06-1
• Molecular Formula: C₇H₆BrNO₄S
• Molecular Weight: 280.1
• Product Categories: blocks;Bromides;NitroCompounds
• Mol File: 94832-06-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 114-117
• Boiling Point: 392.5 °C at 760 mmHg
• Flash Point: 191.2 °C
• Appearance: /
• Density: 1.759 g/cm³
• Vapor Pressure: 5.15E-06mmHg at 25°C
• Refractive Index: 1.592
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE(94832-06-1)
• EPA Substance Registry System: 1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE(94832-06-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 94832-06-1(Hazardous Substances Data)

Usage

General Description

1-Bromo-4-(methylsulphonyl)-2-nitrobenzene is a chemical compound with the molecular formula C7H7BrNO4S. It is a derivative of nitrobenzene, containing a bromine atom and a methylsulphonyl group. 1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE is commonly used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It is also known for its use as a reagent in the synthesis of various organic compounds. However, it is important to handle this chemical with caution, as it is considered to be toxic and harmful if ingested, inhaled, or in contact with the skin. Additionally, it may have adverse effects on the environment if not properly disposed of.

InChI:InChI=1/C7H6BrNO4S/c1-14(12,13)5-2-3-6(8)7(4-5)9(10)11/h2-4H,1H3

Upstream product

• 3466-32-8 4-bromoohenyl methyl sulfone 

Downstream Products

• 942474-24-0 2-bromo-5-(methylsulfonyl)aniline 
• 1186637-36-4 tert-butyl 5-(methylsulfonyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate 
• 1186637-35-3 tert-butyl 2-bromo-5-(methylsulfonyl)phenylcarbamate 
• 1240287-49-3 4-(methylsulfonyl)-2-nitro-1-(prop-1-en-2-yl)benzene 
• 1240287-78-8 1-ethyl-2-iodo-4-methylsulfonylbenzene 
• 1082922-19-7 2-ethyl-5-methylsulfonylaniline 
• 1240287-77-7 4-(methylsulfonyl)-2-nitro-1-vinylbenzene 
• 1240287-22-2 5-(phenylsulfonyl)-2-propylaniline 
• 1240287-21-1 5-(phenylsulfonyl)-2-[(1E)-prop-1-en-1-yl]aniline 
• 1240287-23-3 2-iodo-4-(methylsulfonyl)-1-propylbenzene 
• 1240287-20-0 4-(methylsulfonyl)-2-nitro-1-[(1E)-prop-1-en-1-yl]benzene 
• 1200572-69-5 benzyl 4-{6-[4-(methylsulfonyl)-2-nitrophenyl]-4H-1,3-benzodioxin-2-yl}piperidine-1-carboxylate 

Relevant articles and documents

Preparation method of mesotrione intermediate

The invention relates to a preparation method of a mesotrione intermediate. Methylsulfonyl bromobenzene is taken as an initial raw material, and the method comprises the following steps; first, carrying out a nitration reaction with nitric acid, carrying out extraction treatment on the system after reaction with ethyl acetate and a saturated sodium bicarbonate aqueous solution, and removing an organic phase to obtain a product; then, using DMF as a solvent to carry out a cyanidation reaction with cuprous cyanide at a high temperature, removing the solvent in the system, and separating the product by column chromatography; and hydrolyzing and acidifying the product to obtain a final product namely mesotrione intermediate 2-nitro-4-(methylsulfonyl) benzoic acid. Compared with a traditional synthesis method, the method reduces the use of strong oxidants, has mild reaction conditions, increases the operation safety, is easy in reaction treatment of each step, is beneficial to reaction, andhas a higher yield.