94832-06-1

Usage

Uses

Used in Pharmaceutical Industry:
1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex organic molecules required for drug development.
Used in Agrochemical Industry:
1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE is used as an intermediate in the production of agrochemicals, such as pesticides and herbicides, due to its role in creating essential chemical structures for these products.
Used as a Reagent in Organic Synthesis:
1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE is used as a reagent in the synthesis of various organic compounds, enabling the creation of a wide range of chemical products for different industries.

InChI:InChI=1/C7H6BrNO4S/c1-14(12,13)5-2-3-6(8)7(4-5)9(10)11/h2-4H,1H3

Upstream product

• 3466-32-8 4-bromoohenyl methyl sulfone 

Downstream Products

• 942474-24-0 2-bromo-5-(methylsulfonyl)aniline 
• 1200572-69-5 benzyl 4-{6-[4-(methylsulfonyl)-2-nitrophenyl]-4H-1,3-benzodioxin-2-yl}piperidine-1-carboxylate 
• 1240287-20-0 4-(methylsulfonyl)-2-nitro-1-[(1E)-prop-1-en-1-yl]benzene 
• 1240287-77-7 4-(methylsulfonyl)-2-nitro-1-vinylbenzene 
• 1082922-19-7 2-ethyl-5-methylsulfonylaniline 
• 1240287-78-8 1-ethyl-2-iodo-4-methylsulfonylbenzene 
• 1240287-49-3 4-(methylsulfonyl)-2-nitro-1-(prop-1-en-2-yl)benzene 
• 1186637-35-3 tert-butyl 2-bromo-5-(methylsulfonyl)phenylcarbamate 
• 1186637-36-4 tert-butyl 5-(methylsulfonyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate 
• 1240287-22-2 5-(phenylsulfonyl)-2-propylaniline 
• 1240287-21-1 5-(phenylsulfonyl)-2-[(1E)-prop-1-en-1-yl]aniline 
• 1240287-23-3 2-iodo-4-(methylsulfonyl)-1-propylbenzene 

Relevant academic research and scientific papers

Preparation method of mesotrione intermediate

The invention relates to a preparation method of a mesotrione intermediate. Methylsulfonyl bromobenzene is taken as an initial raw material, and the method comprises the following steps; first, carrying out a nitration reaction with nitric acid, carrying out extraction treatment on the system after reaction with ethyl acetate and a saturated sodium bicarbonate aqueous solution, and removing an organic phase to obtain a product; then, using DMF as a solvent to carry out a cyanidation reaction with cuprous cyanide at a high temperature, removing the solvent in the system, and separating the product by column chromatography; and hydrolyzing and acidifying the product to obtain a final product namely mesotrione intermediate 2-nitro-4-(methylsulfonyl) benzoic acid. Compared with a traditional synthesis method, the method reduces the use of strong oxidants, has mild reaction conditions, increases the operation safety, is easy in reaction treatment of each step, is beneficial to reaction, andhas a higher yield.