94834-01-2

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(6-bromobenzo[d]thiazol-2-yl)ethanone is used as an intermediate for the development of various pharmaceuticals. Its unique structure and functional groups make it a versatile building block in the creation of new drugs with potential therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 1-(6-bromobenzo[d]thiazol-2-yl)ethanone is employed as an intermediate in the synthesis of compounds with pesticidal, herbicidal, or other agricultural applications. Its chemical properties allow for the development of effective products to protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
1-(6-bromobenzo[d]thiazol-2-yl)ethanone is utilized as a building block in organic synthesis, enabling the creation of a wide range of chemical compounds with diverse applications. Its structural features and functional groups facilitate the synthesis of complex molecules for various industries, including materials science, chemical research, and specialty chemicals.
Safety Precautions:
It is crucial to handle 1-(6-bromobenzo[d]thiazol-2-yl)ethanone with care due to its potential health hazards, such as skin and eye irritation. To ensure safety, it should be used in a well-ventilated area, and proper personal protective equipment (PPE), including gloves, goggles, and a mask, should be worn by those working with 1-(6-bromobenzo[d]thiazol-2-yl)ethanone.

Upstream product

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Relevant academic research and scientific papers

Iron-catalyzed tandem oxidative coupling and acetal hydrolysis reaction to prepare formylated benzothiazoles and isoquinolines

The aldehyde group is one of the most versatile intermediates in synthetic chemistry, and the introduction of an aldehyde group into heteroarenes is important for the transformation of molecular structure. Herein, we achieved the direct formylation of benzothiazo/les and isoquinolines. The reaction features a novel iron-catalyzed Minisci-type oxidative coupling process using commercially available 1,3-dioxolane as a formylated reagent followed by acetal hydrolysis without a separation process. The reaction can be performed under exceedingly mild reaction conditions and exhibits broad functional group tolerance.

Carbonylative Acetylation of Heterocycles

Herein, a new procedure for the carbonylative acetylation of heterocycles has been developed. In this process, organic peroxide acts as the methyl source. Various heterocycles were transformed into the corresponding methyl heterocyclic ketones in moderate to good yields.

Compositions containing five-membered unsaturated heterocyclic structure of the α, β unsaturated ketone compound and its preparation method and application

The invention provides alpha, beta unsaturated ketone compounds containing benzo five-membered unsaturated heterocycle structures as well as a preparation method and an application and use of the compounds. The alpha, beta unsaturated ketone compounds containing the benzo five-membered unsaturated heterocycle structures have the structure of a formula (I). In addition, the invention further provides a method for preparing the compounds and a pharmaceutical composition containing the components as active components. In vitro activity tests show that the compounds provided by the invention show a remarkable inhibiting effect on tumor cells. Therefore, the invention lays a foundation for lucubrating and developing anti-tumor medicines in the future and meanwhile further provides a new technical means for treating tumor diseases.

Peroxides as "switches" of dialkyl H-phosphonate: Two mild and metal-free methods for preparation of 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates

Two mild and metal-free methods for the preparation of two kinds of important benzothiazole derivatives, 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates, respectively, were developed. The dialkyl H-phosphonate (RO)2P(O)H exists i

5-SUBSTITUTED IMINOTHIAZINES AND THEIR MONO-AND DIOXIDES AS BACE INHIBITORS,COMPOSITIONS,AND THEIR USE

The present invention discloses certain iminothiazine compounds and mono- and dioxides thereof, including compounds Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomers and said ster

1,3-vs- 1,5-DIPOLAR REACTIVITY OF 1-PHENYLMETHYL-4N-ACETYLIMINO-1H-1,2,4-TRIAZOLIUM BETAIN TOWARD AROMATIC ISOTHIOCYANATES

The title betain I was found to display both 1,3- and 1,5-dipolar reactivity, depending on reaction conditions.Whereas the reaction with aromatic isothiocyanates in nonpolar solvents produced cycloadducts in concerted manner stepwise addition in dimethylf