94850-60-9Relevant academic research and scientific papers
Parallel synthesis of "Click" chalcones as antitubulin agents
Utsintong, Maleeruk,Massarotti, Alberto,Caldarelli, Antonio,Theeramunkong, Sewan
, p. 510 - 516 (2013/07/28)
It has been shown that some chalcones are able to inhibit tubulin polymerization, giving cytotoxicity and destruction of tumoral vasculature. A library of 180 novel chalcone analogs has been synthesized via click chemistry and screened for their cytotoxic
