94851-68-0Relevant academic research and scientific papers
TOTAL SYNTHESIS OF (+/-)-PANICULIDE-A
Jacobi, Peter A.,Kaczmarek, Colleen S.R.,Udodong, Uko E.
, p. 5475 - 5488 (2007/10/02)
An efficient synthesis of the paniculide A precursor 4 has been achieved beginning with 3-methylglutaric anhydride, and utilizing as the key step an intramolecular Diels-Alder reaction of an acetylenic oxazole to give a 2-methoxyfuran.Acid hydrolysis then provided the requisite butenolide ring characteristic of the paniculides.
