94853-03-9

Upstream product

• 931-59-9 benzenesulfenyl chloride 
• 59632-99-4 geranyl 2-tetrahydropyranyl ether 
• 70275-03-5 2-((E)-3,7-Dimethyl-6-phenylsulfanyl-octa-2,7-dienyloxy)-tetrahydro-pyran 
• 70473-31-3 neryl 2-tetrahydropyranyl ether 
• 106-25-2 Nerol 
• 110-87-2 3,4-dihydro-2H-pyran 
• 70238-34-5 2-((Z)-3,7-Dimethyl-6-phenylsulfanyl-octa-2,7-dienyloxy)-tetrahydro-pyran 

Relevant academic research and scientific papers

FACILE FUNCTIONALIZATION OF THE ISOPROPYLIDENE TERMINUS OF ACYCLIC MONOTERPENES BY WAY OF BENZENESULFENYL CHLORIDE ADDITION

Highly site- and regioselective terminal functionalizations of acyclic monoterpenes 1 via benzenesulfenyl chloride addition followed by hydrolysis assisted by silica gel, dehydrochlorination under neutral or weakly basic condition, or dehydrochlorination by strongly basic treatment respectively providing β-hydroxy sulfides 3, terminal methallylic sulfides 4, or vinylsulfides 5 are developed.Conversion of 4 to terminal trans-allylic alcohols 10 via sulfoxides 9 by the Evans procedure is also described.