948552-89-4 Usage
Uses
Used in Pharmaceutical Industry:
6-Hydroxy-3,4-dihydroquinazolin-2(1H)-one is used as a pharmaceutical intermediate for the development of new drugs due to its unique chemical structure and potential pharmacological properties. Its presence in the quinazolinone class suggests that it may have therapeutic applications, particularly in the treatment of various diseases and conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 6-Hydroxy-3,4-dihydroquinazolin-2(1H)-one serves as a key compound for studying its structure-activity relationships and exploring its potential as a lead compound for drug discovery. Its unique structural features allow researchers to investigate its interactions with biological targets and evaluate its efficacy and safety in treating specific medical conditions.
Used in Drug Development:
6-Hydroxy-3,4-dihydroquinazolin-2(1H)-one is utilized in drug development as a starting point for the synthesis of novel therapeutic agents. Its chemical properties and potential pharmacological activities make it a valuable component in the design and synthesis of new drugs with improved efficacy, selectivity, and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 948552-89-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,8,5,5 and 2 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 948552-89:
(8*9)+(7*4)+(6*8)+(5*5)+(4*5)+(3*2)+(2*8)+(1*9)=224
224 % 10 = 4
So 948552-89-4 is a valid CAS Registry Number.
948552-89-4Relevant academic research and scientific papers
An investigation leading to preparation of tetrahydro-quinazoline derivatives involving ureidoalkylation and α-amidoalkylation reactions
Pandey,Mukesh,Kumar, Anilesh,Trivedi, Noopur
experimental part, p. 1910 - 1914 (2009/05/30)
Reaction of an aldehyde with excess equivalent of urea in ethanol affords alkylideno/arylideno-bis-ureas 1 which on condensation with p-aminophenol in acidic medium cyclised to 4-aralkyl-6-hydroxy-2-oxo-1,2,3,4- tetrahydroquinazolines 2. Reaction of 2 with arylamidoalcohols in concentrated H2SO4 results in 4-arylkyl-7-arylamido/imidoalkyl-6- hydroxy-2-oxo-1,2,3,4-tetrahydroquinazolines 3, Compounds 3 have been evaluated for their effect on central nervous system (CNS) and cardiovascular system (CVS).
