948565-46-6Relevant academic research and scientific papers
Synthesis and characterisation of glucosamine-NSAID bioconjugates
Jones, Rachel A.,Thillier, Yann,Panda, Siva S.,Rivera Rosario, Nicole,Hall, C. Dennis,Katritzky, Alan R.
, p. 8325 - 8335 (2015/01/08)
Strategies to couple non-steroidal anti-inflammatory drugs (NSAIDs) to a glucosamine hydrochloride salt via an amino acid linker are investigated and a series of novel NSAID-glucosamine bioconjugates have been prepared. This journal is
Synthesis of D-glucosamine-modified benzo[d][1,2]selenazol-3-(2H)-one derivatives
Zhang, Zhongwei,Ren, Sumei,Wan, Shengbiao,Li, Wei,Jiang, Tao
scheme or table, p. 3438 - 3446 (2011/01/12)
A new class of organoselenium-saccharide derivatives, 2-amino-2-deoxy - D-glucose-modified benzo[d][1,2]selenazol-3-(2H)-one derivatives, has been synthesized via the cyclization reaction of 2-(chloroseleno)benzoyl chloride and O-protected D-glucosamine derivatives. An efficient synthetic method for the preparation of this type of compounds was developed. It has been found that acetone can react with the chloroseleno group under basic conditions, and organoselenium-saccharide derivatives with free hydroxy groups were obtained only when the OH-1 group of the saccharide was protected. Copyright Taylor & Francis Group, LLC.
