948575-74-4Relevant academic research and scientific papers
Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2
Nie, Zhe,Perretta, Carin,Erickson, Philip,Margosiak, Stephen,Almassy, Robert,Lu, Jia,Averill, April,Yager, Kraig M.,Chu, Shaosong
, p. 4191 - 4195 (2008/02/08)
The structure-based design, synthesis, and anticancer activity of novel inhibitors of protein kinase CK2 are described. Using pyrazolo[1,5-a][1,3,5]triazine as the core scaffold, a structure-guided series of modifications provided pM inhibitors with μM-le
