948594-79-4

Basic information

• Product Name: Tert-Butyl Methyl 2-(5-Bromopyrimidin-2-Yl)Malonate
• Synonyms: Tert-Butyl Methyl 2-(5-Bromopyrimidin-2-Yl)Malonate;Tert-Butyl Methyl 2-(5-Bromopyrimidin-2-Yl)Malonate(WX637401)
• CAS NO: 948594-79-4
• Molecular Formula: C12H15BrN2O4
• Molecular Weight: 331.1625
• Mol File: 948594-79-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Tert-Butyl Methyl 2-(5-Bromopyrimidin-2-Yl)Malonate(CAS DataBase Reference)
• NIST Chemistry Reference: Tert-Butyl Methyl 2-(5-Bromopyrimidin-2-Yl)Malonate(948594-79-4)
• EPA Substance Registry System: Tert-Butyl Methyl 2-(5-Bromopyrimidin-2-Yl)Malonate(948594-79-4)

Safety Data

• Hazardous Substances Data: 948594-79-4(Hazardous Substances Data)

Upstream product

• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 42726-73-8 methyl t-butyl malonate 

Downstream Products

• 1114830-16-8 tert-butyl 2-(5-bromopyrimidin-2-yl)acetate 

Relevant articles and documents

RORGAMMA MODULATORS AND USES THEREOF

The present invention provides novel compounds of formula (la) that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases.

QUINOLINE DERIVATIVES FOR TREATING CANCER

The invention concerns quinoline derivatives of Formula (I) or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.