948595-05-9 Usage
Uses
Used in Pharmaceutical Industry:
(R)-2-(Methoxydiphenylmethyl)pyrrolidine is used as a potent analgesic agent for the management of severe pain, due to its strong affinity for the μ-opioid receptors, providing effective pain relief similar to other opioids. However, its high potential for abuse and associated health risks have limited its therapeutic applications.
Used in Research and Development:
R-MDPMP serves as a valuable research tool in the study of opioid receptors and their role in pain management and addiction. It helps scientists understand the mechanisms of action and develop safer and more effective alternatives to traditional opioids.
Check Digit Verification of cas no
The CAS Registry Mumber 948595-05-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,8,5,9 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 948595-05:
(8*9)+(7*4)+(6*8)+(5*5)+(4*9)+(3*5)+(2*0)+(1*5)=229
229 % 10 = 9
So 948595-05-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H21NO/c1-20-18(17-13-8-14-19-17,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17,19H,8,13-14H2,1H3/t17-/m1/s1
948595-05-9Relevant academic research and scientific papers
Addition of the Lithium Anion of Diphenylmethanol Methyl/Methoxymethyl Ether to Nonracemic Sulfinimines: Two-Step Asymmetric Synthesis of Diphenylprolinol Methyl Ether and Chiral (Diphenylmethoxymethyl)amines
Reddy, Arava Amaranadha,Prasad, Kavirayani R.
, p. 10776 - 10785 (2018/09/12)
Addition of the lithium anion generated from diphenylmethanol methyl and methoxymethyl ether to nonracemic sulfinimines afforded the corresponding addition products in excellent diastereoselctivity and yields. Deprotection of the MOM as well as sulfinyl groups rendered the enantiopure (diphenylhydroxymethyl)amines in excellent yields. The procedure was applied for a two-step synthesis of diphenylprolinol, a privileged ligand in asymmetric catalysis.