948644-48-2Relevant academic research and scientific papers
Selective antagonists of mouse trace amine-associated receptor 1 (mTAAR1): Discovery of EPPTB (RO5212773)
Stalder, Henri,Hoener, Marius C.,Norcross, Roger D.
supporting information; experimental part, p. 1227 - 1231 (2011/04/16)
High throughput screening of the Roche compound library identified benzanilides such as 1 and 2 as antagonists of TAAR1. Optimisation of this hit series led to the first selective TAAR1 antagonist (N-(3-Ethoxy-phenyl)-4- pyrrolidin-1-yl-3-trifluoromethyl-
BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS
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Page/Page column 22, (2009/03/07)
The present invention relates to methods of treating CNS disorders with a compound of formula I wherein X, R1, R2, R3, R4, R5, R6, R7, and R8 are as defined in the specification and pharmaceutically acceptable acid addition salts thereof.
