948834-65-9Relevant articles and documents
Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents
Lin, Ronghui,Connolly, Peter J.,Lu, Yanhua,Chiu, George,Li, Shengjian,Yu, Yang,Huang, Shenlin,Li, Xun,Emanuel, Stuart L.,Middleton, Steven A.,Gruninger, Robert H.,Adams, Mary,Fuentes-Pesquera, Angel R.,Greenberger, Lee M.
, p. 4297 - 4302 (2008/02/11)
A series of 3,5-disubstituted pyrazolo[3,4-b]pyridine cyclin-dependent kinase (CDK) inhibitors was synthesized. These compounds showed potent and selective CDK inhibitory activities and inhibited in vitro cellular proliferation in cultured human tumor cel