948837-66-9Relevant academic research and scientific papers
MEMBRANE FUSION INHIBITOR
-
Page/Page column 8-9, (2011/01/12)
The present invention provides a pharmaceutical composition that has excellent safety and targets a different step in the virus propagation cycle than conventional pharmaceutical compositions, applicable as an antiviral agent. A pharmaceutical composition
Enhanced anti-influenza A virus activity of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: Effect of alkyl chain length
Mori, Shuichi,Miyake, Shinya,Kobe, Takayoshi,Nakaya, Takaaki,Fuller, Stephen D.,Kato, Nobuo,Kaihatsu, Kunihiro
experimental part, p. 4249 - 4252 (2009/04/07)
A series of fatty acid monoester derivatives of (-)-epigallocatechin-3-O-gallate (EGCG) were prepared by one-pot lipase-catalyzed transesterification. The introduction of long alkyl chains enhanced anti-influenza A/PR8/34 (H1N1) virus activity 24-fold relative to native EGCG.
