948856-18-6Relevant academic research and scientific papers
4-Amino-5-substituted-3(2H)-pyridazinones as orally active antinociceptive agents: Synthesis and studies on the mechanism of action
Giovannoni, Maria Paola,Cesari, Nicoletta,Vergelli, Claudia,Graziano, Alessia,Biancalani, Claudio,Biagini, Pierfrancesco,Ghelardini, Carla,Vivoli, Elisa,Dal Piaz, Vittorio
, p. 3945 - 3953 (2008/02/11)
A number of 4-amino-5-vinylpyridazinones and 4-amino-5-heterocyclic- pyridazinones were synthesized and tested for their analgesic activity. Many of these compounds, tested at doses of 3-20 mg kg-1 po, showed good antinociceptive activity, redu
