94887-81-7Relevant academic research and scientific papers
Electrochemistry of Organic Cations. V. Synthesis of 3,10-Diaza-tricyclo2,6>dodeca-4,8-diene Derivatives by a Two-Step Electrochemical Reduction of Pyridinium Ions
Pragst, F.,Koeppel, H.,Walkhoff, E.,Boche, E.
, p. 665 - 674 (2007/10/02)
A series of 1-substituted 2,4,6-trimethylpyridinium ions 1a-1k is cathodically dimerized in alkaline medium.The bis--derivatives 2 obtained or their isomers 4 are submitted to a further cathodic reduction in aqueous acetic acid at mercury or lead electrodes to form 3,10-diaza-tricyclo2,6>dodeca-4,8-dienes 6 by an intramolecular coupling reaction between the 2- and 2'-carbon atoms of the dihydropyridine rings.Depending on R1 the yields of 6 are 65-80percent (R1 = alkyl or substituted alkyl) or 3,5-5percent (R1 = aryl).
