948909-59-9Relevant articles and documents
Novel inhibitor for fibroblast growth factor receptor tyrosine kinase
Kammasud, Naparat,Boonyarat, Chantana,Tsunoda, Satoshi,Sakurai, Hiroaki,Saiki, Ikuo,Grierson, David S.,Vajragupta, Opa
, p. 4812 - 4818 (2007)
NP603, the 6-dimethoxy phenyl indolin-2-one, was designed as FGF receptor 1 inhibitor by computational study. NP603 was synthesized and found to be more active against endothelial proliferation of HUVEC after the rhFGF-2 stimulation than SU6668 with minim