948913-21-1

Basic information

• Product Name: C₂₉H₃₂ClFN₆O₄
• Synonyms: C₂₉H₃₂ClFN₆O₄
• CAS NO: 948913-21-1
• Molecular Weight: 583.062
• Mol File: 948913-21-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₉H₃₂ClFN₆O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₃₂ClFN₆O₄(948913-21-1)
• EPA Substance Registry System: C₂₉H₃₂ClFN₆O₄(948913-21-1)

Safety Data

• Hazardous Substances Data: 948913-21-1(Hazardous Substances Data)

Upstream product

• 119951-96-1 (3-chloro-4-fluoro-phenyl)-carbamic acid tert-butyl ester 

Downstream Products

• 948913-22-2 C₂₉H₃₄ClFN₆O₂ 

Relevant articles and documents

PROCESSES FOR SYNTHESIZING 7-ALKYNYL-4-AMINOQUINAZOLINES AND A RELATED INTERMEDIATE

A process for synthesizing 7-alkynyl-4-aminoquinazolines from 7-haloquinazolines is disclosed. In one specific synthesis, 4-[N-3-chloro-4-fluorophenyl)]-7- [3-methyl-3-(4-methyl-l-piperazinyl)-l- butynyl]-6-[N-inethyl acrylamide] quinazoline is prepared from 7-chloro-6-nitro-3H-quinazolin-4-one. Also disclosed is an intermediate useful in the syntheses of 7-alkynyl-4-ammoquinaozolines and a process for making the intermediate. The 7-alkynyl-4-aminoquinaozolines prepared by processes of the invention are useful as pharmaceutically active compounds.