94899-23-7Relevant academic research and scientific papers
Controlled ring-opening polymerization of α-amino acid N-carboxy-anhydride by frustrated amine/borane Lewis pairs
Zhang, Hongyuan,Nie, Yanzhao,Zhi, Xinmei,Du, Haifeng,Yang, Jing
, p. 5155 - 5158 (2017/07/12)
In this communication, we presented a novel strategy to control the ROP of α-amino acid N-carboxy-anhydrides using the concept of frustrated Lewis pairs (FLPs). An FLP intermediate containing an interaction between the bulky borane Lewis acid and the amine groups of the propagation chain end is essential to accomplish the polypeptide synthesis with well-defined structures under mild conditions.
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic
Balboni, Gianfranco,Fiorini, Stella,Baldisserotto, Anna,Trapella, Claudio,Sasaki, Yusuke,Ambo, Akihiro,Marczak, Ewa D.,Lazarus, Lawrence H.,Salvadori, Severo
experimental part, p. 5109 - 5117 (2009/08/16)
Some reference opioids containing the Dmt-Tic pharmacophore, especially the δ agonists H-Dmt-Tic-GlyNH-Ph (1) and H-Dmt-TiC-NH-(S)CH(CH 2-COOH)-Bid (4) (UFP-512) were evaluated for the influence of the substitution of Gly with aspartic acid, it
