949007-45-8Relevant academic research and scientific papers
Synthesis of 4-Azido-N-acetylhexosamine Uridine Diphosphate Donors: Clickable Glycosaminoglycans
Zhang, Xing,Green, Dixy E.,Schultz, Victor L.,Lin, Lei,Han, Xiaorui,Wang, Ruitong,Yaksic, Alexander,Kim, So Young,Deangelis, Paul L.,Linhardt, Robert J.
, p. 9910 - 9915 (2017)
Unnatural chemically modified nucleotide sugars UDP-4-N3-GlcNAc and UDP-4-N3-GalNAc were chemically synthesized for the first time. These unnatural UDP sugar products were then tested for incorporation into hyaluronan, heparosan, or
Synthesis of UDP-GlcNAc derivatives modified at OH-4 as potential chain-terminators of chitin biosynthesis
Muller, Thierry,Danac, Ramona,Ball, Lucy,Gurr, Sarah J.,Fairbanks, Antony J.
, p. 1299 - 1307 (2008/02/08)
A series of UDP-GlcNAc derivatives and precursors that have been modified at the 4-position were synthesised from N-acetyl glucosamine as potential chain terminators of chitin biosynthesis. None of the UDP-derivatives or the precursors tested displayed an
OLIGOSACCHARIDE BIOSYNTHESIS INHIBITORS
-
Page/Page column 50-51, (2010/11/28)
This invention provides a method for inhibiting oligosaccharide biosynthesis in vivo and in vitro comprising the steps of administering at least one monosaccharide derivative, wherein the hydroxyl group which is the glycosyl acceptor (i.e. the active hydr
