949100-26-9

Basic information

• Product Name: 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol
• Synonyms: 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol;4-((1H-Benzo[d]iMidazol-1-yl)Methyl)piperidin-4-ol;4-Piperidinol, 4-(1H-benzimidazol-1-ylmethyl)-
• CAS NO: 949100-26-9
• Molecular Formula: C₁₃H₁₇N₃O
• Molecular Weight: 231
• Mol File: 949100-26-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol(949100-26-9)
• EPA Substance Registry System: 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol(949100-26-9)

Safety Data

• Hazardous Substances Data: 949100-26-9(Hazardous Substances Data)

Usage

Description

4-Benzoimidazol-1-ylmethyl-piperidin-4-ol is a chemical compound that features a unique structure combining a benzimidazole ring with a piperidine ring. 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol holds potential pharmaceutical applications due to the known biological activities of its constituent parts. The benzimidazole moiety is recognized for its potential anticancer and antifungal properties, while the piperidine ring is a prevalent structural element in numerous pharmaceuticals and natural products. The fusion of these two rings positions 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol as a promising candidate for drug development and medicinal chemistry research, with the potential to address a variety of diseases. However, further investigation is required to elucidate its full biological activity and therapeutic potential.

Uses

Used in Pharmaceutical Development:
4-Benzoimidazol-1-ylmethyl-piperidin-4-ol is utilized as a novel drug candidate for the treatment of various diseases due to its unique structure and the potential biological activities associated with its benzimidazole and piperidine components.
Used in Anticancer Research:
In the field of oncology, 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol is used as a potential anticancer agent, leveraging the known anticancer properties of the benzimidazole ring. Its structure may allow it to target and inhibit specific cancer-related pathways, offering a new approach to cancer treatment.
Used in Antifungal Applications:
4-Benzoimidazol-1-ylmethyl-piperidin-4-ol is also considered for use as an antifungal agent, capitalizing on the benzimidazole moiety's established antifungal capabilities, which could be beneficial in treating a range of fungal infections.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 4-Benzoimidazol-1-ylmethyl-piperidin-4-ol serves as a subject of study for understanding its interaction with biological targets and its potential to be optimized for specific therapeutic uses, including the development of new drugs with improved efficacy and safety profiles.

Upstream product

• 1357011-85-8 4-(1H-benzo[d]imidazol-1-ylmethyl)-1-benzylpiperidin-4-ol 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 51-17-2 benzoimidazole 
• 19867-34-6 N-benzyl-1-oxa-6-azaspiro[2,5]-octane 

Downstream Products

• 1357011-91-6 N-[3-[4-(1H-benzo[d]imidazol-1-ylmethyl)-4-hydroxypiperidin-1-yl]-1-phenylpropyl]-4-fluorobenzamide 

Relevant articles and documents

Synthesis and biological evaluation of novel piperidin-4-ol derivatives

A series of novel piperidin-4-ol derivatives were designed, synthesized, and evaluated for potential treatment of HIV. The compounds were obtained via an efficient synthetic route in excellent yields and have been characterized by 1H NMR, 13C NMR, MS, and elemental analysis. The CCR5 antagonistic activities of the compounds have also been evaluated.