94911-63-4Relevant academic research and scientific papers
MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
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Paragraph 001013, (2017/08/01)
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
Novel indazoles for the treatment and prophylaxis of respiratory syncytial virus infection
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Paragraph 0449-0450, (2016/08/17)
The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5, R7, A1, A2 and A3 are as described herein, compositions including the compounds and methods of using the compounds.
Novel indazoles for the treatment and prophylaxis of respiratory syncytial virus infection
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Paragraph 0448; 0449, (2015/06/17)
The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, R5, R7, A1, A2 and A3 are as described herein, compositions including the compounds and methods of using the compounds.
NOVEL INDAZOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION
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Page/Page column 91; 92, (2014/02/15)
The invention provides novel compounds having the general formula: formula (I) wherein R1, R2, R3, R4, R5, R7, A1, A2 and A3 are as described herein, compositions including the compounds and methods of using the compounds.
Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans
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Page/Page column 90, (2009/01/20)
The Invention relates to compounds having an antiparasitic activity, and to their use as a drug, in particular as a drug for the prevention and/or treatment of parasitic diseases caused by apicomplexans. The invention also relates to pharmaceutical compositions containing those compounds.
HETEROCYCLIC-NMDA ANTAGONISTS
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, (2008/06/13)
The present invention is directed to a class of 3-phosphono-piperidine and pyrrolidine derivatives and their use as NMDA antagonists.
Synthesis of Ethyl 2,3-Bis(ethoxycarbonyl)-1H-pyrrole-1-propionate
Roeder, Erhard,Wiedenfeld, Helmut,Bourauel, Thomas
, p. 1117 - 1120 (2007/10/02)
Ethyl 2,3-bis(ethoxycarbonyl)-1H-pyrrole-1-propionate (7) can easily be obtained in high yields from ethyl 4-iodobutyrate (1) via reaction with dibenzylamine and diethyl oxalate, catalytic debenzylation to diethyl cis-2,3-pyrrolidinedicarboxylate (5), sub
