949148-86-1

Upstream product

• 186581-53-3 diazomethane 
• 949148-83-8 (3E,5S,6R,7S)-7-(tert-butyl-diphenyl-silanyloxy)-6-methoxy-3,5-dimethyl-oct-3-enoic acid methyl ester 
• 949148-84-9 (E)-(S)-3-(dimethyl-phenyl-silanyl)-3-methyl-hex-4-enoic acid methyl ester 

Downstream Products

• 949148-87-2 (6S,7R,8S,E)-8-(tert-butyldiphenylsilyloxy)-N-((1S,2S)-1-hydroxy-1-phenylpropan-2-yl)-7-methoxy-N,4,6-trimethylnon-4-enamide 
• 949148-89-4 (2S,6S,7R,8S,E)-8-(tert-butyldiphenylsilyloxy)-7-methoxy-2,4,6-trimethylnon-4-en-1-ol 
• 949148-98-5 C₂₉H₄₂O₃Si 
• 949148-81-6 tert-butyl((2S,3R,4S,5E,8S,9E)-10-iodo-3-methoxy-4,6,8-trimethyldeca-5,9-dien-2-yloxy)diphenylsilane 
• 949148-93-0 2-((2R,5S,6S)-6-((2E,4E,6S,8E,10S,11R,12S)-12-(tert-butyldiphenylsilyloxy)-11-methoxy-6,8,10-trimethyltrideca-2,4,8-trien-2-yl)-5-methyltetrahydro-2H-pyran-2-yl)acetonitrile 
• 949148-94-1 methyl 2-((2R,5S,6S)-6-((2E,4E,6S,8E,10S,11R,12S)-12-(tert-butyldiphenylsilyloxy)-11-methoxy-6,8,10-trimethyltrideca-2,4,8-trien-2-yl)-5-methyltetrahydro-2H-pyran-2-yl)acetate 
• 142861-00-5 2-((2R,5S,6S)-6-((S,2E,4E)-7-((2R,3R)-3-((2R,3R,4R)-4-hydroxy-3-methoxypentan-2-yl)-2-methyloxiran-2-yl)-6-methylhepta-2,4-dien-2-yl)-5-methyltetrahydro-2H-pyran-2-yl)acetic acid 

Relevant academic research and scientific papers

Total synthesis of herboxidiene/GEX 1A

A convergent enantioselective synthesis of herboxidiene/GEX 1A (1) is described that features a double stereodifferentiating crotylation, [4 + 2] annulation, and a silicon-based sp2-sp2 cross-coupling to assemble the conjugated diene