949154-53-4

Upstream product

• 125228-00-4 (S)-tert-butyl (3-(3,4-bis(benzyloxy)phenyl)-1-amino-1-oxopropan-2-yl)carbamate 

Downstream Products

• 949154-55-6 4-methyl-benzoic acid 4-((S)-2-tert-butoxycarbonylamino-2-carbamoylethyl)-2-(4-methylbenzoyloxy)-phenyl ester 
• 1246370-76-2 (S)-tert-butyl (1-amino-3-(3,4-bis(pivaloyloxy)phenyl)-1-oxopropan-2-yl)carbamate 

Relevant academic research and scientific papers

Design, synthesis and biological evaluation of l-dopa amide derivatives as potential prodrugs for the treatment of Parkinson's disease

A range of amide derivatives of l-dopa were synthesized and investigated for their pharmacological activity and their ability to be converted to l-dopa using the unilaterally 6-hydroxydopamine (6-OHDA)-lesioned rat, as an experimental model of Parkinson's

AMINO ACID DERIVATIVES

Compounds of formula (I) are active as dopaminergic compounds or as compounds which or as compounds which diminish the symptoms of dopamine deficiency.: wherein: R1 and R2 are independently selected from -C(=O)R5 or -C(=O)OR5; or one of R1 and R2 is hydrogen and the other is -C(=O)R5 or -C(=O)OR5; R3 and R4 are independently selected from hydrogen, optionally substituted C1-C6 alkyl, C3-C6 cycloalkyl, C2-C6 alkenyl, or C2-C6 alkynyl, -CH2Q, -C(=O)R5, -C(=O)OR5, - C(=O)NR5R6, or R5 is hydrogen or optionally substituted C1-C6 alkyl or -CH2Q; R6 is hydrogen or optionally substituted C1-C6 alkyl Or -CH2Q; and Q is an optionally substituted monocyclic carbocyclic or heterocyclyl ring of 3 to 6 ring atoms.