949259-77-2Relevant academic research and scientific papers
A facile synthesis of 1-chloro-2,2,2-trifluoroethyl sulfides
Pustovit, Yuriy,Alexeenko, Anatoliy,Trofymchuk, Sergii,Lukin, Oleg,Tolmachev, Andrey A.
, p. 1159 - 1165 (2010)
A facile synthesis of structurally diverse 1-chloro-2,2,2-trifluoroethyl sulfides from readily available 1-bromo-1-chloro-2,2,2-trifluoroethane (Halothane) and various aliphatic and aromatic thiols in the presence of sodium dithionite/sodium bicarbonate is described. The synthetic utility of the prepared sulfides is illustrated by the synthesis of biologically potent heterocycles and by their electrophilic reactions with thiophene.
