94935-97-4Relevant academic research and scientific papers
Biomimetic synthesis of grossularines-1
Miyake, Fumiko Y.,Yakushijin, Kenichi,Horne, David A.
, p. 3280 - 3282 (2005)
(Chemical Equation Presented) Like a sea squirt: An efficient biomimetic synthesis of the antitumor α-carboline marine alkaloids grossularine-1 (1) and N,N-didesmethylgrossularine-1 (2) is based on a novel oxidative dimerization of 2-amino-4-(3-indolyl)imidazole.
SYNTHESIS OF GROSSULARINES-1 AND ANALOGS THEREOF AND METHOD OF USE
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Page/Page column 6, (2008/06/13)
In one embodiment of the present invention, a synthesis of grossularine-1 and N,N-didesmethylgrossularine-1 2 and analogs thereof based on a novel oxidative dimerization-electrocyclization sequence of 2-amino-4-(3-indolyl)imidazoles derived from oxotryptamine 3 is described.
