94938-03-1

Usage

Uses

Used in Organic Chemistry:
1-METHYL-2-PHENYL-1H-IMIDAZOLE-5-CARBALDEHYDE is used as a reagent and intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique chemical properties allow it to be a key component in the creation of a wide range of products.
Used in Material Science:
1-METHYL-2-PHENYL-1H-IMIDAZOLE-5-CARBALDEHYDE has potential applications in the field of material science. Its ability to engage in various chemical reactions makes it a promising candidate for the development of new materials with specific properties.
Used in Drug Discovery:
1-METHYL-2-PHENYL-1H-IMIDAZOLE-5-CARBALDEHYDE also has potential applications in drug discovery. Its versatility in chemical reactions can contribute to the development of new pharmaceutical compounds, potentially leading to breakthroughs in medicine.

Upstream product

• 68282-47-3 2-phenyl-1H-imidazole-4-carbaldehyde 
• 74-88-4 methyl iodide 
• 616-38-6 carbonic acid dimethyl ester 
• 161670-81-1 (1-methyl-2-phenyl-1H-imidazol-5-yl)methanol 
• 77-78-1 dimethyl sulfate 
• 161670-65-1 1-methyl-2-phenyl-5-trifluoroacetylimidazole 
• 161670-80-0 ethyl 1-methyl-2-phenyl-1H-imidazole-5-carboxylate 
• 14119-99-4 4-trifluoroacetyl-3-methyl-2-phenyl-1,3-oxazol-3-ium-5-olate 
• 2568-34-5 N-benzoyl-N-methylglycine 

Relevant academic research and scientific papers

PIPERIDINE-CONTAINING COMPOUNDS AND USE THEREOF

A method for preventing and/or treating a metabolic disease, cerebrovascular disease, etc. which comprises administering to a mammal an effective amount of the compound of the formula (I) wherein all symbols have the same meanings as defined in the specification; a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. And a novel compound of the formula (I-1): wherein all symbols have the same meanings as defined in the specification; a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof has an anti-diabetic effect and a neuroprotective effect. Accordingly, the compound of the formula (I) and the compound of the formula (I-1) are useful in a method for preventing and/or treating for a metabolic disease such as diabetes, cerebrovascular disease such as stroke, etc.

3-‘4-HETEROCYCLYL -1,2,3,-TRIAZOL-1-YL!-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES

Disclosed compounds of formula (I), which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Convenient synthesis of 5-trifluoroacetylated imidazoles by ring transformation of mesoionic 1,3-oxazolium-5-olates

Mesoionic 4-trifluoroacetyl-1,3-oxazolium-5-olates (1), obtained from the reaction of N-acyl-N-alkylglycines (2) with trifluoroacetic anhydride, react with amidines to give 5-trifluoroacetylimidazoles (3) in moderate yield. The novel ring transformations of 1 into 3 occur via an initial attack of amidines on the C-2 position of the ring.

Synthesis, structure, and neuroprotective properties of novel imidazolyl nitrones

A new series of imidazolyl nitrones spin traps has been synthesized and evaluated pharmacologically. The salient structural feature of these molecules is the presence of an imidazole moiety substituted by aromatic or heteroaromatic cycles. This connectivi

A Novel Ring Transformation of Mesoionic 1,3-Oxazolium-5-olates into 5-Trifluoroacetylated and 5-Perfluoroacylated Imidazoles by Reaction with Amidines

Treatment of mesoionic 1,3-oxazolium-5-olates with amidines causes a novel ring transformation affording 5-trifluoroacetyl- and 5-perfluoroacyl-imidazoles in moderate yields.