94943-13-2

Basic information

• Product Name: 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one
• CAS NO: 94943-13-2
• Molecular Formula: C₁₈H₂₀O₅
• Molecular Weight: 316.3484
• Mol File: 94943-13-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 505.6°C at 760 mmHg
• Flash Point: 182.2°C
• Density: 1.18g/cm³
• Vapor Pressure: 4.79E-11mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one(94943-13-2)
• EPA Substance Registry System: 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one(94943-13-2)

Safety Data

• Hazardous Substances Data: 94943-13-2(Hazardous Substances Data)

Usage

General Description

1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one is a chemical compound with the molecular formula C18H20O5. It is a member of the chalcone family and is known for its antioxidant and anti-inflammatory properties. 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one is commonly used in pharmaceutical and cosmetic industries due to its potential therapeutic and skincare applications. Research has shown that 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one may have potential health benefits, including reducing the risk of chronic diseases and improving skin health. However, further studies are needed to fully understand its therapeutic potential and safety profile.

Upstream product

• 829-20-9 2',4'-dimethoxyacetophenone 
• 123-11-5 4-methoxy-benzaldehyde 
• 18493-30-6 1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 77412-32-9 α-hydroxychalcone 

Downstream Products

• 117614-88-7 (+/-)-1-hydroxy-1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl) propan-2-one 
• 77412-32-9 α-hydroxychalcone 

Relevant articles and documents

α-HYDROXYDIHYDROCHALCONES AND RELATED 1,3-DIARYLPROPAN-2-ONES FROM XANTHOCERCIS ZAMBESIACA

Key Word Index-Xanthocercis zambesiaca; Leguminosae; 7,8-dioxyisoflavonoids; α-hydroxydihydrochalcones; 1,3-diarylpropan-2-ones.Abstract-In addition to some previously described 7,8-dioxy-isoflavonoids and 2-benzylbenzofuran-3(2H)-ones the heartwood of Xanthocercis zambesiaca has been shown to contain 7,8,3'-trihydroxy-4'-methoxyisoflavone.These are accompained by the novel α,3,4,4'-tetrahydroxy-2'-methoxydihydrochalcone and its 3-deoxy analogue, the latter of which presumably served as biogenetic precursor for the unique 1-hydroxy-3-(4-hydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl) propan-2-one and its 1-deoxy analogue.Such possible biosynthetic relationship was demonstrated by the facile in vitro transformations of the appropriate α-hydroxydihydrochalcone into the different 1,3-diarylpropan-2-ones.

A Novel α-Hydroxydihydrochalcone from the Heartwood of Pterocarpus angolensis D.C.: Absolute Configuration, Synthesis, Photochemical Transformations, and Conversion into α-Methyldeoxybenzoins

The absolute configuration of (αR)-α,2'-dihydroxy-4,4'-dimethoxydihydrochalcone from the heartwood of Pterocarpus angolensis D.C. is established.Its structure is substantiated by synthesis and by photochemical conversion of its α-O-tosyl derivative into an α-tosyloxymethyldeoxybenzoin and hence to the α-methyldeoxybenzoin analogue.The photochemical step also leads, amongst others, to α-hydroxymethyldeoxybenzoin, β-hydroxydihydrochalcone, and 2-benzylbenzofuran-3-one analogues depending on the conditions the photolysis.